Publications

2024

Ye, S. C., Cheung, C. C., Lauder, E., Grunau, B., Moghaddam, N., van Diepen, S., Holmes, D. T., Sekhon, M. S., Christenson, J., Tallon, J. M., & Fordyce, C. B. (2024). Association of admission serum sodium and outcomes following out-of-hospital cardiac arrest. American Heart Journal, 268, 29–36. https://doi.org/10.1016/J.AHJ.2023.11.011

Lingawi, S., Hutton, J., Khalili, M., Shadgan, B., Christenson, J., Grunau, B., & Kuo, C. (2024). Cardiorespiratory Sensors and Their Implications for Out-of-Hospital Cardiac Arrest Detection: A Systematic Review. Annals of biomedical engineering, 10.1007/s10439-024-03442-y. Advance online publication. https://doi.org/10.1007/s10439-024-03442-y
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2023

Morrison, L. J., Sandroni, C., Grunau, B., Parr, M., Macneil, F., Perkins, G. D., Aibiki, M., Censullo, E., Lin, S., Neumar, R. W., Brooks, S. C.,Organ Donation After Out-of-Hospital Cardiac Arrest: A Scientific Statement From the International Liaison Committee on Resuscitation. Resuscitation. 2023;190:109864. doi:10.1016/j.resuscitation.2023.109864
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Hutton, J., Grunau, B., Asamoah-Boaheng, M., Christenson, J., Khalili, M., Kuo, C., Lingawi, S., Puyat, J. H., Shadgan, B., & Sobolev, B. (2023). The Effect of Recognition on Survival after Out-of-Hospital Cardiac Arrest and Implications for Biosensor Technologies. Resuscitation, 109906. Advance online publication. https://doi.org/10.1016/j.resuscitation.2023.109906

Mok, V., Brebner, C., Yap, J., Asamoah-Boaheng, M., Hutton, J., Haines, M., Scheuermeyer, F., Kawano, T., Christenson, J., & Grunau, B. (2023). Non-prescription drug-associated out-of-hospital cardiac arrest: Changes in incidence over time and the odds of receiving resuscitation. Resuscitation, 110107. https://doi.org/10.1016/J.RESUSCITATION.2023.110107

Heidet, M., Benjamin Leung, K. H., Bougouin, W., Alam, R., Frattini, B., Liang, D., Jost, D., Canon, V., Deakin, J., Hubert, H., Christenson, J., Vivien, B., Chan, T., Cariou, A., Dumas, F., Jouven, X., Marijon, E., Bennington, S., Travers, S., … Grunau, B. (2023). Improving EMS response times for out-of-hospital cardiac arrest in urban areas using drone-like vertical take-off and landing air ambulances: An international, simulation-based cohort study. Resuscitation, 193. https://doi.org/10.1016/j.resuscitation.2023.109995

Armour, R., Ghamarian, E., Helmer, J., Buick, J. E., Thorpe, K., Austin, M., Bacon, J., Boutet, M., Cournoyer, A., Dionne, R., Goudie, M., Lin, S., Welsford, M., & Grunau, B. (2023). Impact of the COVID-19 pandemic on Canadian emergency medical system management of out-of-hospital cardiac arrest: A retrospective cohort study. Resuscitation, 194. https://doi.org/10.1016/j.resuscitation.2023.110054

Brebner, C., Asamoah-Boaheng, M., Zaidel, B., Yap, J., Scheuermeyer, F., Mok, V., Christian, M., Kawano, T., Singh, L., van Diepen, S., Christenson, J., & Grunau, B. (2023). The association of tibial vs. humeral intraosseous vascular access with patient outcomes in adult out-of-hospital cardiac arrests. Resuscitation, 193. https://doi.org/10.1016/j.resuscitation.2023.110031

Hoiland, R. L., Robba, C., Menon, D. K., Citerio, G., Sandroni, C., & Sekhon, M. S. (2023). Clinical targeting of the cerebral oxygen cascade to improve brain oxygenation in patients with hypoxic–ischaemic brain injury after cardiac arrest. Intensive Care Medicine 2023 49:9, 49(9), 1062–1078. https://doi.org/10.1007/S00134-023-07165-X

Sekhon, M. S., Stukas, S., Hirsch-Reinshagen, V., Thiara, S., Schoenthal, T., Tymko, M., McNagny, K. M., Wellington, C., & Hoiland, R. (2023). Neuroinflammation and the immune system in hypoxic ischaemic brain injury pathophysiology after cardiac arrest. The Journal of Physiology. https://doi.org/10.1113/JP284588

Heidet M, Grunau B, Vaillancourt C, Baert V; CanROC, Gr-RéAC, ReACanROC investigators. Trends in out-of-hospital cardiac arrest across the world: Additional data from the CanROC and RéAC national registries. Resuscitation. 2023;187:109786. doi:10.1016/j.resuscitation.2023.109786

Cournoyer, A., Grunau, B., Cheskes, S., Vaillancourt, C., Segal, E., de Montigny, L., de Champlain, F., Cavayas, Y. A., Albert, M., Potter, B., Paquet, J., Lessard, J., Chauny, J. M., Morris, J., Lamarche, Y., Marquis, M., Cossette, S., Castonguay, V., & Daoust, R. (2023). Clinical outcomes following out-of-hospital cardiac arrest: The minute-by-minute impact of bystander cardiopulmonary resuscitation. Resuscitation, 185, 109693. https://doi.org/10.1016/j.resuscitation.2023.109693

Awad E, Fordyce CB, Grunau B, Christenson J, Helmer J, Humphries K. One-year survival after out-of- hospital cardiac arrest: Sex-based survival analysis in a Canadian population. J Am Coll Emerg Physicians Open. 2023;4(3):e12957. Published 2023 May 9. doi:10.1002/emp2.12957

Raschdorf, K., Mohseni, A., Hogle, K., Cheung, A., So, K., Manouchehri, N., Khalili, M., Lingawi, S., Grunau, B., Kuo, C., Christenson, J., & Shadgan, B. (2023). Evaluation of transcutaneous near-infrared spectroscopy for early detection of cardiac arrest in an animal model. Scientific reports, 13(1), 4537. https://doi.org/10.1038/s41598-023-31637-1

Asamoah-Boaheng M, Goldfarb DM, Karim ME, O’Brien SF, Wall N, Drews SJ, Barakauskas V, Jassem AN, Grunau B, The relationship between anti-spike SARS CoV-2 antibody levels and risk of breakthrough Covid-19 infection among fully vaccinated adults. J Infect Dis. 2023:jiac403. Doi:10.1093/infdis/jiac403.

Khan, L., Hutton, J., Yap, J., Dodek, P., Scheuermeyer, F., Asamoah-Boaheng, M., Heidet, M., Wall, N., Fordyce, C. B., van Diepen, S., Christenson, J., & Grunau, B. (2023). The association of the post-resuscitation on-scene interval and patient outcomes after out-of-hospital cardiac arrest. Resuscitation, 188, 109753. https://doi.org/10.1016/j.resuscitation.2023.109753

Asamoah-Boaheng, M., Goldfarb, D. M., Karim, M. E., OBrien, S. F., Wall, N., Drews, S. J., Barakauskas, V., Jassem, A. N., & Grunau, B. (2023). The Relationship Between Anti-Spike SARS-CoV-2 Antibody Levels and Risk of Breakthrough COVID-19 Among Fully Vaccinated Adults. The Journal of infectious diseases, 227(3), 339–343. https://doi.org/10.1093/infdis/jiac403

Asamoah-Boaheng, M., Goldfarb, D., Prusinkiewicz, M. A., Golding, L., Karim, M. E., Barakauskas, V., Wall, N., Jassem, A. N., Marquez, A. C., MacDonald, C., O’Brien, S. F., Lavoie, P., & Grunau, B. (2023). Determining the Optimal SARS-CoV-2 mRNA Vaccine Dosing Interval for Maximum Immunogenicity. Cureus, 15(1), e34465. https://doi.org/10.7759/cureus.34465

2022

Fordyce, C. B., Kramer, A. H., Ainsworth, C., Christenson, J., Hunter, G., Kromm, J., Lopez Soto, C., Scales, D. C., Sekhon, M., van Diepen, S., Dragoi, L., Josephson, C., Kutsogiannis, J., Le May, M. R., Overgaard, C. B., Savard, M., Schnell, G., Wong, G. C., Belley-Côté, E., … Teitelbaum, J. (2023). Neuroprognostication in the Post Cardiac Arrest Patient: A Canadian Cardiovascular Society Position Statement. The Canadian journal of cardiology, 39(4), 366–380. https://doi.org/10.1016/j.cjca.2022.12.014

Grunau, B., Singh, G., Bělohlávek, J., Yannopoulos, D., Tonna, J. E., Hutin, A., Nagpal, D., Cournoyer, A., & van Diepen, S. (2023). A Second Chance for Survival: Clinical Trial Evidence, Eligibility, and Barriers to Implementation of ECPR for Out-of-Hospital Cardiac Arrest. The Canadian journal of cardiology, 39(4), 381–384. https://doi.org/10.1016/j.cjca.2022.12.006

Chai, J., Fordyce, C. B., Guan, M., Humphries, K., Hutton, J., Christenson, J., & Grunau, B. (2023). The association of duration of resuscitation and long-term survival and functional outcomes after out-of-hospital cardiac arrest. Resuscitation, 182, 109654. https://doi.org/10.1016/j.resuscitation.2022.11.020

Hutton J, Lingawi S, Puyat JH, Kuo, C., Shadgan, B., Christenson, J., & Grunau, B. Sensor technologies to detect out-of-hospital cardiac arrest: A systematic review of diagnostic test performance. Resusc Plus. 2022;11:100277. Published 2022 Jul 27. doi:10.1016/j.resplu.2022.100277

Grunau, B., Tom, J., Asamoah-Boaheng, M., O’Brien, S. F., Drews, S. J., Sediqi, S., Lavoie, P. M., Barakauskas, V., & Goldfarb, D. M. (2022). Sensitivity of the Elecsys Nucleocapsid Assay for the Detection of Preceding SARS-CoV-2 Infections. Open forum infectious diseases, 9(8), ofac349. https://doi.org/10.1093/ofid/ofac349

Grunau, B., O’Brien, S. F., Kirkham, T. L., Helmer, J., Demers, P. A., Asamoah-Boaheng, M., Drews, S. J., Karim, M. E., Srigley, J. A., Sediqi, S., O’Neill, D., Drennan, I. R., & Goldfarb, D. M. (2022). A Prospective Observational Cohort Comparison of SARS-CoV-2 Seroprevalence Between Paramedics and Matched Blood Donors in Canada During the COVID-19 Pandemic. Annals of emergency medicine, 80(1), 38–45. https://doi.org/10.1016/j.annemergmed.2022.03.009

Fagan, A., Grunau, B., Caddell, A., Gould, J., Rayner-Hartley, E., Lamarche, Y., Singh, G., Nagpal, D., & Slessarev, M. (2022). CEPP: Canadian Extracorporeal Life Support (ECLS) Protocol Project. CJC open, 4(6), 520–531. https://doi.org/10.1016/j.cjco.2022.02.005

Leung, K., Grunau, B., Al Assil, R., Heidet, M., Liang, L. D., Deakin, J., Christenson, J., Cheskes, S., & Chan, T. (2022). Incremental gains in response time with varying base location types for drone-delivered automated external defibrillators. Resuscitation, 174, 24–30. https://doi.org/10.1016

Heidet, M., Hubert, H., Grunau, B. E., Cheskes, S., Baert, V., Fraticelli, L., Freyssenge, J., Lecarpentier, E., Stitt, A., Tallon, J. M., Tazarourte, K., Truong, C., Vaillancourt, C., Vilhelm, C., Wysocki, K., Christenson, J., El Khoury, C., & Gr-ReAC and CanROC investigators (2022). Rationale, development and implementation of the ReACanROC registry for out-of-hospital cardiac arrests in France and Canada. Emergency medicine journal : EMJ, 39(7), 547–553. https://doi.org/10.1136/emermed-2020-211073/j.resuscitation.2022.03.013

Heidet M, Freyssenge J, Claustre C, Deakin J, Helmer J, Thomas-Lamotte B, Wohl M, Liang D, Hubert H, Baert V, Vilhelm C, Fraticelli L, Mermet E, Benhamed A, Revaux F, Lecarpentier E, Debaty G, Tazaroute K, Cheskes S, Christenson J, El Khoury C, Grunau B. ReAC, CanROC, ReACanROC Investigators. Association between location of out-of-hospital cardiac arrest, on-scene socioeconomic status, and accessibility to public automated defibrillators in two large metropolitan areas in Canada and France. Resuscitation. 2022. 181: 97 – 109. Doi:10.1016/j.resuscitation.2022.10.016

Shinar Z, Grunau B. ECPR for in- and out-of-hospital cardiac arrest: Siblings or distant cousins?.Resuscitation. 2022 Feb;171:105-106. doi: 10.1016/j.resuscitation.2021.12.018.

Roston TM, So DY, Liu S, Fordyce CB, Grunau B, Jentzer JC, Bagai A, Luk A, Goodman SG, van Diepen S. Leveraging existing STEMI care networks to regionalize cardiogenic shock systems of care: efforts to expand the scope could improve shock outcomes. Can J Cardiol. 2022 Nov 16:S0828-282X 01040-6. Doi: 10.1016/j.cjca.2022.110.005

Liang LD, Chan TCY, Leung KHB, Scheuermeyer FX, Chakrabarti S, Andelius L, Deakin J, Heidet M, Fordyce CB, Helmer J, Christenson J, Al Assil R, Grunau B. Utilization and cost effectiveness of school and community center AED deployment models in Canadian cities. Resuscitation. 2022. 172: 194 – 200. Doi:1016/j.resuscitation.2021.12.035

Mackay MH, Chruscicki A, Christenson J, Cairns JA, Lee T, Turgeon R, Tallon JM, Helmer JM, Singer J, Wong GC, Fordyce CB. Association of prehospital time intervals and clinical outcomes in ST-elevation myocardial infarction patients. J Am Coll Emerg Physicians Open. 2022 3:e12764 doi: 10.1002/emp2.12764.

Yap J, Haines M, Nowroozpoor A, Armour R, Luongo A, Sidhu G, Scheuermeyer FX, Hutton J, Helmer J, Bolster J, Puyat J, Christenson J, Grunau B. Rationale for withholding professional resuscitation in emergency medical system-attended out of hospital cardiac arrest. Resuscitation. 2022; 170: 201- 206. Doi: 10.1016/j.resuscitation.2021.12.010

Yap J, Helmer J, Gessaroli M, Hutton J, Khan L, Scheuermeyer FX, Wall N, Bolster J, van Diepen S, Puyat J, Asamoah-Boaheng M, Straight R, Christenson J, Grunau B. Performance of the medical priority dispatch system in correctly classifying out-of-hospital cardiac arrests as appropriate for resuscitation. Resuscitation 2022 181: 123- 131. Doi: 10.1016/ jresuscitation.2022.22.001.

Fordyce CB, Grunau BE, Guan M, Hawkins NM, Lee MK, Helmer JS, Wong GC, Humphries KH, Christenson J. Long-term mortality, readmission, and resource utilization among hospitalized survivors of out-of-hospital cardiac arrest. Can J Cardiol. 2022; 38: 1719 – 1728. Doi:10.10.1016/j.cjca.2022.08.225

Liang LD, Chan TCY, Leung KHB, Scheuermeyer F, Chakrabarti S, Andelius L, Deakin J, Heidet M, Fordyce CB, Helmer J, Christenson J, Al Assil R, Grunau B. Utilization and cost-effectiveness of school and community center AED deployment models in Canadian cities. Resuscitation. 2022 Jan 11:S0300-9572(21)00542-6. doi: 10.1016/j.resuscitation.2021.12.035. Online ahead of print.

Grunau, B., Goldfarb, D. M., Asamoah-Boaheng, M., Golding, L., Kirkham, T. L., Demers, P. A., & Lavoie, P. M. (2022). Immunogenicity of Extended mRNA SARS-CoV-2 Vaccine Dosing Intervals. JAMA, 327(3), 279–281. https://doi.org/10.1001/jama.2021.21921
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Hutton G, Kawano T, Scheuermeyer FX, Panchal AR, Asamoah-Boaheng M, Christenson J, Grunau B. Out-of-hospital cardiac arrests terminated without full resuscitation attempts: Characteristics and regional variability. Resuscitation. Resuscitation. 2022 Jan 22;172:47-53. doi: 10.1016/j.resuscitation.2022.01.013. Online ahead of print.

Asamoah-Boaheng M, Grunau B, Karim ME, Jassem AN, Bolster J, Marquez AC, Scheuermeyer FX, Goldfarb DM. Are higher antibody levels against seasonal human coronaviruses associated with a more robust humoral immune response after SARS-CoV-2 vaccination? Front Immunol. Sep 8; doi: 10.3387/fimmu.2022.954093.

Grunau B, Tom J, Asamoah-Boaheng M, O’Brien SF, Drews SJ, Sediqi S, Lavoie PM, Barakauskas V, Goldfarb DM. Sensitivity of the elecsys nucleocapsid assay for the detection of preceding SARS-CoV infections. Open Forum Infect Dis. 2022; 9: ofac349 doi:10.1093/ofid/ofac34

Asamoah-Boaheng M, Goldfarb DM, Karim ME, O’Brien SF, Wall N, Drews SJ, Barakauskas V, Jassem AN, Grunau B, The relationship between anti-spike SARS CoV-2 antibody levels and risk of breakthrough Covid-19 infection among fully vaccinated adults. J Infect Dis. 2022:jiac403. Doi:10.1093/infdis/jiac403.

Liang LD, Leung KHB, Chan TCY, Deakin J, Heidet M, Meckler G, Scheuermeyer FX, Sanatani S, Christenson J, Grunau B. Pediatric and out-of-hospital cardiac arrest incidence within and near public schools in British Columbia. Missed opportunities for systemic AED deployment strategies. Resuscitation. 2022 181:20-25. Doi: 10.1016/jresuscitation.2022.09.020

Grunau, B., Asamoah-Boaheng, M., Lavoie, P. M., Karim, M. E., Kirkham, T. L., Demers, P. A., Barakauskas, V., Marquez, A. C., Jassem, A. N., O’Brien, S. F., Drews, S. J., Haig, S., Cheskes, S., & Goldfarb, D. M. (2021). A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, ciab938. Advance online publication. https://doi.org/10.1093/cid/ciab938
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Grunau, B., O’Brien, S. F., Kirkham, T. L., Helmer, J., Demers, P. A., Asamoah-Boaheng, M., Drews, S. J., Karim, M. E., Srigley, J. A., Sediqi, S., O’Neill, D., Drennan, I. R., & Goldfarb, D. M. (2022). A Prospective Observational Cohort Comparison of SARS-CoV-2 Seroprevalence Between Paramedics and Matched Blood Donors in Canada During the COVID-19 Pandemic. Annals of emergency medicine, S0196-0644(22)00188-3. Advance online publication. https://doi.org/10.1016/j.annemergmed.2022.03.009

Marshall RA, Morton JS, Luchkanych AMS, El Karsh Y, El Karsh Z, Morse C, Tomczak CR, Grunau BE, Olver TD. Left ventricle chest compression improves EtCO2, blood pressure, and cerebral blood velocity in a swine model of cardiac arrest and cardiopulmonary resuscitation. Resusc Plus. 2022 Nov 14;12:100326. Doi: 10.1016/jresplu.2022.100326

Leung, K., Grunau, B., Al Assil, R., Heidet, M., Liang, L. D., Deakin, J., Christenson, J., Cheskes, S., & Chan, T. (2022). Incremental gains in response time with varying base location types for drone-delivered automated external defibrillators. Resuscitation, 174, 24–30. Advance online publication. https://doi.org/10.1016/j.resuscitation.2022.03.013

Yap, J., Scheuermeyer, F. X., van Diepen, S., Barbic, D., Straight, R., Wall, N., Asamoah-Boaheng, M., Christenson, J., & Grunau, B. (2022). Temporal trends of suicide-related non-traumatic out-of-hospital cardiac arrest characteristics and outcomes with the COVID-19 pandemic. Resuscitation plus, 9, 100216. https://doi.org/10.1016/j.resplu.2022.100216
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Grunau, B., Golding, L., Prusinkiewicz, M. A., Asamoah-Boaheng, M., Armour, R., Marquez, A. C., Jassem, A. N., Barakauskas, V., O’Brien, S. F., Drews, S. J., Haig, S., Lavoie, P. M., & Goldfarb, D. M. (2022). Comparative 6-Month Wild-Type and Delta-Variant Antibody Levels and Surrogate Neutralization for Adults Vaccinated with BNT162b2 versus mRNA-1273. Microbiology spectrum, e0270221. Advance online publication. https://doi.org/10.1128/spectrum.02702-21

Lane, D. J., Grunau, B., Kudenchuk, P., Dorian, P., Wang, H. E., Daya, M. R., Lupton, J., Vaillancourt, C., Okubo, M., Davis, D., Rea, T., Yannopoulos, D., Christenson, J., & Scheuermeyer, F. (2022). Bayesian analysis of amiodarone or lidocaine versus placebo for out-of-hospital cardiac arrest. Heart (British Cardiac Society), heartjnl-2021-320513. Advance online publication. https://doi.org/10.1136/heartjnl-2021-320513

Asamoah-Boaheng, M., Goldfarb, D. M., Barakauskas, V., Kirkham, T. L., Demers, P. A., Karim, M. E., Lavoie, P. M., Marquez, A. C., Jassem, A. N., Jenneson, S., MacDonald, C., & Grunau, B. (2022). Evaluation of the Performance of a Multiplexed Serological Assay in the Detection of SARS-CoV-2 Infections in a Predominantly Vaccinated Population. Microbiology spectrum, 10(1), e0145421. https://doi.org/10.1128/spectrum.01454-21

Awad EM, Humphries KH, Grunau BE, Norris CM, Christenson JM. Predictors of neurological outcome after out-of-hospital cardiac arrest: sex-based analysis: do males derive greater benefit from hypothermia management than females? Int J Emerg Med. 2022 15: 43. Doi: 10.1186/s12245-022-0447-z

2021

Yap, J., Haines, M., Nowroozpoor, A., Armour, R., Luongo, A., Sidhu, G., Scheuermeyer, F., Hutton, J., Helmer, J., Bolster, J., Puyat, J., Christenson, J., & Grunau, B. Rationale for Withholding Professional Resuscitation in Emergency Medical System-attended Out-of-Hospital Cardiac Arrest. Resuscitation, 170, 201–206. https://doi.org/10.1016/j.resuscitation.2021.12.010

Nichol G, Zhuang R, Russell R, Holcomb, J. B., Kudenchuk, P. J., Aufderheide, T. P., Morrison, L., Sugarman, J., Ornato, J. P., Callaway, C. W., Vaillancourt, C., Bulger, E., Christenson, J., Daya, M. R., Schreiber, M., Idris, A., Podbielski, J. M., Sopko, G., Wang, H., Wade, C. E., … May, S. (2021). Variation in time to notification of enrollment and rates of withdrawal in resuscitation trials conducted under exception from informed consent. Resuscitation. 2021. doi:10.1016/J.RESUSCITATION.2021.07.039

Awad EM, Humphries KH, Grunau BE, Christenson JM. Premenopausal-aged females have no neurological outcome advantage after out-of-hospital cardiac arrest: A multilevel analysis of North American populations. Resuscitation. 2021;166:58-65. doi:10.1016/j.resuscitation.2021.06.024

Awad E, Humphries K, Grunau B, Besserer F, Christenson J. The effect of sex and age on return of spontaneous circulation and survival to hospital discharge in patients with out of hospital cardiac arrest: A retrospective analysis of a Canadian population. Resusc Plus. 2021;5:100084. Published 2021 Feb 6. doi:10.1016/j.resplu.2021.100084
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Al Assil R, Singer J, Heidet M, Fordyce, C. B., Scheuermeyer, F., Diepen, S. V., Sekhon, M., Leung, K., Stenstrom, R., Christenson, J., & Grunau, B. The association of pH values during the first 24 h with neurological status at hospital discharge and futility among patients with out-of-hospital cardiac arrest. Resuscitation. 2021;159:105-114. doi:10.1016/J.RESUSCITATION.2020.12.017

Besserer F, Kawano T, Dirk J. Meckler, G., Tijssen, J. A., DeCaen, A., Scheuermeyer, F., Beno, S., Christenson, J., Grunau, B., & Canadian Resuscitation Outcomes Consortium (2021). /j.resuscitation.2021.08.005 The association of intraosseous vascular access and survival among pediatric patients with out-of-hospital cardiac arrest. Resuscitation. 2021;167:49-57. doi:10.1016/j.resuscitation.2021.08.005

Heidet M, Hubert H, Grunau BE, Cheskes, S., Baert, V., Fraticelli, L., Freyssenge, J., Lecarpentier, E., Stitt, A., Tallon, J. M., Tazarourte, K., Truong, C., Vaillancourt, C., Vilhelm, C., Wysocki, K., Christenson, J., El Khoury, C., & Gr-ReAC and CanROC investigators Rationale, development and implementation of the ReACanROC registry for out-of-hospital cardiac arrests in France and Canada. Emerg Med J. 2021. doi:10.1136/emermed-2020-211073

Vaillancourt C, Charette M, Naidoo S., Taljaard, M., Church, M., Hodges, S., Leduc, S., Christenson, J., Cheskes, S., Dainty, K., Feldman, M., Goldstein, J., Tallon, J., Helmer, J., Sibley, A., Spidel, M., Blanchard, I., Garland, J., Cyr, K., Brehaut, J., Thiruganasambandamoorthy, V. Multi-centre implementation of an Educational program to improve the Cardiac Arrest diagnostic accuracy of ambulance Telecommunicators and survival outcomes for sudden cardiac arrest victims: the EduCATe study design and methodology. BMC Emerg Med. 2021;21(1). doi:10.1186/S12873-021-00416-4
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Ho K, Lauscher HN, Stewart K, Abu-Laban, R. B., Scheuermeyer, F., Grafstein, E., Christenson, J., & Sundhu, S. Integration of virtual physician visits into a provincial 8-1-1 health information telephone service during the COVID-19 pandemic: a descriptive study of HealthLink BC Emergency iDoctor-in-assistance (HEiDi). CMAJ Open. 2021;9(2):E635-E641. Published 2021 Jun 15. doi:10.9778/cmajo.20200265
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Fergusson NA, Hoiland RL, Thiara S, Foster, D., Gooderham, P., Rikhraj, K., Grunau, B., Christenson, J., Ainslie, P. N., Griesdale, D., & Sekhon, M. S Goal-Directed Care Using Invasive Neuromonitoring Versus Standard of Care After Cardiac Arrest: A Matched Cohort Study. Crit Care Med. 2021;49(8):1333-1346. doi:10.1097/CCM.0000000000004945

Saczkowski R, Kuzak N, Grunau B, Schulze C. Extracorporeal life support rewarming rate is associated with survival with good neurological outcome in accidental hypothermia. Eur J cardio-thoracic Surg Off J Eur Assoc Cardio-thoracic Surg. 2021;59(3):593-600. doi:10.1093/ejcts/ezaa385

Richardson ASC, Tonna JE, Nanjayya V, Nixon, P., Abrams, D. C., Raman, L., Bernard, S., Finney, S. J., Grunau, B., Youngquist, S. T., McKellar, S. H., Shinar, Z., Bartos, J. A., Becker, L. B., Yannopoulos, D., Bˇelohlávek, J., Lamhaut, L., & Pellegrino, V.Extracorporeal Cardiopulmonary Resuscitation in Adults. Interim Guideline Consensus Statement From the Extracorporeal Life Support Organization. ASAIO J. Published online February 2021. doi:10.1097/MAT.0000000000001344

Grunau B, Kawano T, Rea TD, Okubo, M., Scheuermeyer, F. X., Reynolds, J. C., Heidet, M., Drennan, I. R., Cheskes, S., Fordyce, C. B., Twaites, B., & Christenson, J. Emergency medical services employing intra-arrest transport less frequently for out-of-hospital cardiac arrest have higher survival and favorable neurological outcomes. Resuscitation. 2021;168:27-34. doi:10.1016/j.resuscitation.2021.09.004

Grunau B, Helmer J, Lee S, Acker, J., Deakin, J., Armour, R., Tallon, J., Jenneson, S., Christenson, J., & Scheuermeyer, F. X. Decrease in emergency medical services utilization during early stages of the COVID‑19 pandemic in British Columbia. Can J Emerg Med. 2021;23(2):237-241.doi.org/10.1007/s43678-020-00062-y
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Grunau B, Shemie SD, Wilson LC, Dainty, K. N., Nagpal, D., Hornby, L., Lamarche, Y., van Diepen, S., Kanji, H. D., Gould, J., Saczkowski, R., & Brooks, S. C. Current Use, Capacity, and Perceived Barriers to the Use of Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest in Canada. CJC Open. 2021. doi:10.1016/j.cjco.2020.11.005

Schmicker RH, Nichol G, Kudenchuk P., Christenson, J., Vaillancourt, C., Wang, H. E., Aufderheide, T. P., Idris, A. H., & Daya, M. R. CPR compression strategy 30:2 is difficult to adhere to, but has better survival than continuous chest compressions when done correctly. Resuscitation. 2021;165:31-37. doi:10.1016/j.resuscitation.2021.05.027

Senaratne JM, Sandhu R, Barnett CF, Grunau B, Wong GC, van Diepen S. Approach to Ventricular Arrhythmias in the Intensive Care Unit. J Intensive Care Med. 2021;36(7):731-748. doi:10.1177/0885066620912701

Grunau B, Dainty K, MacRedmond R,McDonald, K., Sasaki, A., Sarti, A. J., Shemie, S. D., Cheung, A., & Gill, J.A qualitative exploratory case series of patient and family experiences with ECPR for out-of-hospital cardiac arrest. Resusc plus. 2021;6:100129. doi:10.1016/j.resplu.2021.100129

Grunau B, Bashir J, Cheung A, Boone, R., McDonald, K., Scheuermeyer, F., Singer, J., Jenneson, S., Straight, R., Twaites, B., Harris, L., Haig, S., Harris, D., Vandegriend, R., Kanji, H., & Christenson, J.A pragmatic parallel group implementation study of a prehospital-activated ECPR protocol for refractory out-of-hospital cardiac arrest. Resuscitation. 2021;167:22-28. doi:10.1016/j.resuscitation.2021.08.004

Grunau B, Rea T. A goal to transform public access defibrillation to all access defibrillation. Resuscitation. 2021;162:417-419. doi:10.1016/j.resuscitation.2021.02.018

2020

Sawyer, K. N., Humbert, A., Leroux, B. G., Nichol, G., Kudenchuk, P. J., Daya, M. R., Grunau, B., Wang, H. E., Ornato, J. P., Rittenberger, J. C., Aufderheide, T. P., Wittwer, L., Colella, M. R., Austin, M., Kawano, T., Egan, D., Richmond, N., Vithalani, V. D., Scales, D., Baker, A. J. Relationship Between Duration of Targeted Temperature Management, Ischemic Interval, and Good Functional Outcome From Out-of-Hospital Cardiac Arrest. Crit Care Med. 2020;48(3):370-377. doi:10.1097/CCM.0000000000004160

Drebit, S., Eggers, K., Archibald, C., Abu-Laban, R., Ho, K., Khazei, A., Lindstrom, R., Marsden, J., Martin, E., & Christenson, J. Evaluation of Patient Engagement in a Clinical Emergency Care Network: Findings From the BC Emergency Medicine Network. J Patient Exp. 2020;7(6):937-940. doi:10.1177/2374373520925721
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Daya, M. R., Leroux, B. G., Dorian, P., Rea, T. D., Newgard, C. D., Morrison, L. J., Lupton, J. R., Menegazzi, J. J., Ornato, J. P., Sopko, G., Christenson, J., Idris, A., Mody, P., Vilke, G. M., Herdeman, C., Barbic, D., Kudenchuk, P. J., & Resuscitation Outcomes Consortium Investigators Survival after intravenous versus intraosseous amiodarone, lidocaine, or placebo in out-of-hospital shock-refractory cardiac arrest. Circulation. Published online 2020:188-198. doi:10.1161/CIRCULATIONAHA.119.042240
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Barbic, D., Duncan, K., Trainor, R., Ertel, E. A., Enos, M. K., Philips, H., Besserer, F., Grunau, B., Kestler, A., Christenson, J., & Scheuermeyer, F. X. A Survey of the Public’s Ability to Recognize and Willingness to Intervene in Out-of-hospital Cardiac Arrest and Opioid Overdose. Acad Emerg Med. 2020;27(4):305-308. doi:10.1111/ACEM.13916
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Grunau, B., Bal, J., Scheuermeyer, F., Guh, D., Dainty, K. N., Helmer, J., Saini, S., Chakrabarti, A., Brar, N., Sidhu, N., Barbic, D., Christenson, J., & Chakrabarti, S. Bystanders are less willing to resuscitate out-of-hospital cardiac arrest victims during the COVID-19 pandemic. Resusc Plus. 2020;4:100034. doi:10.1016/J.RESPLU.2020.100034
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Grunau, B., Kime, N., Leroux, B., Rea, T., Van Belle, G., Menegazzi, J. J., Kudenchuk, P. J., Vaillancourt, C., Morrison, L. J., Elmer, J., Zive, D. M., Le, N. M., Austin, M., Richmond, N. J., Herren, H., & Christenson, J. Association of Intra-arrest Transport vs Continued On-Scene Resuscitation with Survival to Hospital Discharge among Patients with Out-of-Hospital Cardiac Arrest. JAMA – J Am Med Assoc. 2020;324(11):1058-1067. doi:10.1001/JAMA.2020.14185
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Zhao, Y., Sivaswamy, A., Lee, M. K., Izadnegahdar, M., Chu, A., Ferreira-Legere, L. E., Humphries, K. H., & Udell, J. A. High-Sensitivity Cardiac Troponin—Optimizing the Diagnosis of Acute Myocardial Infarction/Injury in Women (CODE-MI): Rationale and design for a multicenter, stepped-wedge, cluster-randomized trial. Am Heart J. 2020;229:18-28. doi:10.1016/J.AHJ.2020.06.013

Rowell, S. E., Meier, E. N., McKnight, B., Kannas, D., May, S., Sheehan, K., Bulger, E. M., Idris, A. H., Christenson, J., Morrison, L. J., Frascone, R. J., Bosarge, P. L., Colella, M. R., Johannigman, J., Cotton, B. A., Callum, J., McMullan, J., Dries, D. J., Tibbs, B., Richmond, N. J., … Schreiber, M. A. Effect of Out-of-Hospital Tranexamic Acid vs Placebo on 6-Month Functional Neurologic Outcomes in Patients with Moderate or Severe Traumatic Brain Injury. JAMA – J Am Med Assoc. 2020;324(10):961-974. doi:10.1001/JAMA.2020.8958
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Scheuermeyer, F. X., Norena, M., Innes, G., Grunau, B., Christenson, J., Grafstein, E., Barbic, D., & Barrett, T. Decision aid for early identification of acute underlying illness in emergency department patients with atrial fibrillation or flutter. Can J Emerg Med. 2020;22(3):301-308. doi:10.1017/CEM.2019.454
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Sinden, S., Heidet, M., Scheuermeyer, F., Kawano, T., Helmer, J. S., Christenson, J., & Grunau, B. The association of scene-access delay and survival with favourable neurological status in patients with out-of-hospital cardiac arrest. Resuscitation. 2020;155:211-218. Accessed October 1, 2021. http://www.ncbi.nlm.nih.gov/pubmed/32522699

Bartos, J. A., Grunau, B., Carlson, C., Duval, S., Ripeckyj, A., Kalra, R., Raveendran, G., John, R., Conterato, M., Frascone, R. J., Trembley, A., Aufderheide, T. P., & Yannopoulos, D. Improved Survival With Extracorporeal Cardiopulmonary Resuscitation Despite Progressive Metabolic Derangement Associated With Prolonged Resuscitation. Circulation. 2020;141(11):877-886. doi:10.1161/CIRCULATIONAHA.119.042173

Heidet, M., Fraticelli, L., Grunau, B., Cheskes, S., Baert, V., Vilhelm, C., Hubert, H., Tazarourte, K., Vaillancourt, C., Tallon, J., Christenson, J., El Khoury, C., & Gr-ReAC CanROC investigators ReACanROC: Towards the creation of a France–Canada research network for out-of-hospital cardiac arrest. Resuscitation. 2020;152:133-140. doi:10.1016/J.RESUSCITATION.2020.05.008

Vaillancourt, C., Petersen, A., Meier, E. N., Christenson, J., Menegazzi, J. J., Aufderheide, T. P., Nichol, G., Berg, R., Callaway, C. W., Idris, A. H., Davis, D., Fowler, R., Egan, D., Andrusiek, D., Buick, J. E., Bishop, T. J., Colella, M. R., Sahni, R., Stiell, I. G., Cheskes, S. The impact of increased chest compression fraction on survival for out-of-hospital cardiac arrest patients with a non-shockable initial rhythm. Resuscitation. 2020;154:93-100. doi:10.1016/J.RESUSCITATION.2020.06.016

Heidet, M., Da Cunha, T., Brami, E., Mermet, E., Dru, M., Simonnard, B., Lecarpentier, E., Chollet-Xémard, C., Bergeron, C., Khalid, M., Grunau, B., Marty, J., & Audureau, E. EMS Access Constraints And Response Time Delays For Deprived Critically Ill Patients Near Paris, France. Health Aff (Millwood). 2020;39(7):1175-1184. doi:10.1377/hlthaff.2019.00842

Grunau, B., Humphries, K., Stenstrom, R., Pennington, S., Scheuermeyer, F., van Diepen, S., Awad, E., Al Assil, R., Kawano, T., Brooks, S., Gu, B., & Christenson, J. Public access defibrillators: Gender-based inequities in access and application. Resuscitation. 2020;150:17-22. Accessed October 1, 2021. https://pubmed.ncbi.nlm.nih.gov/32126247/

Nguyen, M. L., Gause, E., Mills, B., Tonna, J. E., Alvey, H., Saczkowski, R., Grunau, B., Becker, L. B., Gaieski, D. F., Youngquist, S., Gunnerson, K., England, P., Hamilton, J., Badulak, J., Mandell, S. P., Bulger, E. M., Johnson, N. J. Traumatic and hemorrhagic complications after extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest. Resuscitation. 2020;157:225-229. doi:10.1016/j.resuscitation.2020.09.035

Guy, A., Kawano, T., Besserer, F., Scheuermeyer, F., Kanji, H. D., Christenson, J., & Grunau, B. The relationship between no-flow interval and survival with favourable neurological outcome in out-of-hospital cardiac arrest: Implications for outcomes and ECPR eligibility. Resuscitation. 2020;155:219-225.

Fernando SM, Grunau B, Brodie D. Just the Facts: Extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest. CJEM. 2020;22(6):760-763. doi:10.1017/cem.2020.450

Awad E, Christenson J, Grunau B, Tallon J, Humphries K.
Sex differences in out-of-hospital cardiac arrest interventions within the province of British Columbia, Canada. Resuscitation. 2020;148:128-134.

2019

Stanger D, Kawano T, Malhi N, et al. Door-to-Targeted Temperature Management Initiation Time and Outcomes in Out-of-Hospital Cardiac Arrest: Insights From the Continuous Chest Compressions Trial. J Am Heart Assoc. 2019;8(9). doi:10.1161/JAHA.119.012001

Grunau B, MacRedmond R, Gill J. A Promising Therapy in Jeopardy. Circulation. 2019;139(4):425-427. doi:10.1161/CIRCULATIONAHA.118.035674

Scheuermeyer FX, Wong H, Barrett TW, et al. Active management of atrial fibrillation or flutter in emergency department patients with renal impairment is associated with a higher risk of adverse events and treatment failure. CJEM. 2019;21(3):352-360. doi:10.1017/cem.2018.475
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Kylie Dyson, Siobhan P Brown, Susanne May, Karen Smith, Rudolph W Koster, Stefanie G Beesems, Markku Kuisma, Ari Salo, Judith Finn, Fritz Sterz, Alexander Nürnberger, Laurie J Morrison, Theresa M Olasveengen, Clifton W Callaway, Sang Do Shin, Jan-Thorsten Gräsner, Mohamud Daya, Matthew Huei-Ming Ma, Johan Herlitz, Anneli Strömsöe, Tom P Aufderheide, Siobhán Masterson, Henry Wang, Jim Christenson, Ian Stiell, Gary M Vilke, Ahamed Idris, Chika Nishiyama, Taku Iwami, Graham Nichol. International variation in survival after out-of-hospital cardiac arrest: A validation study of the Utstein template. Resuscitation. Volume 138, May 2019, Pages 168-181.DOI: 10.1016/j.resuscitation.2019.03.018

Brian Grunau, Frank Scheuermeyer, Takahisa Kawano, Jennie S Helmer, Bobby Gu, Scott Haig, Jim Christenson. North American validation of the Bokutoh criteria for withholding professional resuscitation in non-traumatic out-of-hospital cardiac arrest. Resuscitation Volume 135, February 2019, Pages 51-56.

Brian Grunau, Takahisa Kawano, Frank Scheuermeyer, John Tallon, Joshua Reynolds, Floyd Besserer, David Barbic, Steven Brooks, Jim Christenson. Early advanced life support attendance is associated with improved survival and neurologic outcomes after non-traumatic out-of-hospital cardiac arrest in a tiered prehospital response system. Resuscitation Volume 135, February 2019, Pages 137-144. DOI: 10.1016/j.resuscitation.2018.12.003

Frank FX Scheuermeyer, Grant Innes, Eric Grafstein, Ryan Chard, Stephanie Vandenberg, Jay Cheyne, Rob Cheyne, Jim Christenson, Brian Grunau, David Barbic, Stephen W Smith. Emergency Department Patients With a Prolonged Corrected QT Interval Do Not Have Increased Thirty‐day Mortality. Academic emergency medicine. Volume 27(7) 818-822. July 2019.

Brian Grunau, Takahisa Kawano, Frank X. Scheuermeyer, Ian Drennan, Christopher B. Fordyce, Sean van Diepen, Joshua Reynolds, Steve Lin, Jim Christenson. The Association of the Average Epinephrine Dosing Interval and Survival With Favorable Neurologic Status at Hospital Discharge in Out-of-Hospital Cardiac Arrest. Published online Annals of Emergency Medicine June 24 2019. https://doi.org/10.1016/j.annemergmed.2019.04.031

2018

Kawano T, Grunau B, Scheuermeyer FX, et al. Intraosseous Vascular Access Is Associated With Lower Survival and Neurologic Recovery Among Patients With Out-of-Hospital Cardiac Arrest. Ann Emerg Med. Published online January 2018. doi:10.1016/j.annemergmed.2017.11.015

Time to Epinephrine Administration and Survival From Nonshockable Out-of-Hospital Cardiac Arrest Among Children and Adults. Circulation. 2018;137(19):2032-2040. doi:10.1161/CIRCULATIONAHA.117.033067

Sun, T., Guy, A., Sidhu, A., Finlayson, G., Grunau, B., Ding, L., Harle, S., Dewar, L., Cook, R., & Kanji, H. D.Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for emergency cardiac support. J Crit Care. 2018;44. doi:10.1016/j.jcrc.2017.10.011

Barbic D, Klinkenberg B, Grunau B, Christenson J. Do neighbourhoods in Vancouver and surrounding areas demonstrate different rates of bystander CPR and survival for out-of-hospital cardiac arrest? Can J Emerg Med. 2018;20(1). doi:10.1017/cem.2016.384
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Salcido, D. D., Schmicker, R. H., Kime, N., Buick, J. E., Cheskes, S., Grunau, B., Zellner, S., Zive, D., Aufderheide, T. P., Koller, A. C., Herren, H., Nuttall, J., Sundermann, M. L., Menegazzi, J. J Effects of intra-resuscitation antiarrhythmic administration on rearrest occurrence and intra-resuscitation ECG characteristics in the ROC ALPS trial. Resuscitation. 2018;129. doi:10.1016/j.resuscitation.2018.05.028

Kurz MC, Schmicker RH, Leroux B, Kurz, M. C., Schmicker, R. H., Leroux, B., Nichol, G., Aufderheide, T. P., Cheskes, S., Grunau, B., Jasti, J., Kudenchuk, P., Vilke, G. M., Buick, J., Wittwer, L., Sahni, R., Straight, R., Wang, H. E., & ROC Investigators. Advanced vs. Basic Life Support in the Treatment of Out-of-Hospital Cardiopulmonary Arrest in the Resuscitation Outcomes Consortium. Resuscitation. Published online April 2018. doi:10.1016/j.resuscitation.2018.04.031

Randhawa, V. K., Grunau, B. E., Debicki, D. B., Zhou, J., Hegazy, A. F., McPherson, T., & Nagpal, A. D. Cardiac Intensive Care Unit Management of Patients After Cardiac Arrest: Now the Real Work Begins. Can J Cardiol. 2018;34(2):156-167. doi:10.1016/j.cjca.2017.11.013

Scheuermeyer, F. X., DeWitt, C., Christenson, J., Grunau, B., Kestler, A., Grafstein, E., Buxton, J., Barbic, D., Milanovic, S., Torkjari, R., Sahota, I., & Innes, G. Safety of a Brief Emergency Department Observation Protocol for Patients With Presumed Fentanyl Overdose. Ann Emerg Med. 2018;72(1):1–8.e1. doi:10.1016/j.annemergmed.2018.01.054

Grunau, B., Puyat, J., Wong, H., Scheuermeyer, F. X., Reynolds, J. C., Kawano, T., Singer, J., Dick, W., & Christenson, J. Gains of Continuing Resuscitation in Refractory Out-of-hospital Cardiac Arrest: A Model-based Analysis to Identify Deaths Due to Intra-arrest Prognostication. Prehospital Emerg care Off J Natl Assoc EMS Physicians Natl Assoc State EMS Dir. 2018;22(2):198-207. doi:10.1080/10903127.2017.1356412

Grunau, B., Singer, J., Lee, T., Scheuermeyer, F. X., Straight, R., Schlamp, R., Wand, R., Dick, W. F., Connolly, H., Pennington, S., & Christenson, J. A Local Sensitivity Analysis of the Trial of Continuous or Interrupted Chest Compressions during Cardiopulmonary Resuscitation: Is a Local Protocol Change Required? Cureus. 2018;10(9):e3386. Accessed October 1, 2021. http://www.ncbi.nlm.nih.gov/pubmed/30524914
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Grunau, B., Hornby, L., Singal, R. K., Christenson, J., Ortega-Deballon, I., Shemie, S. D., Bashir, J., Brooks, S. C., Callaway, C. W., Guadagno, E., & Nagpal, D. Extracorporeal Cardiopulmonary Resuscitation for Refractory Out-of-Hospital Cardiac Arrest: The State of the Evidence and Framework for Application. Can J Cardiol. 2018;34(2):146-155. doi:10.1016/j.cjca.2017.08.015

Okubo, M., Schmicker, R. H., Wallace, D. J., Idris, A. H., Nichol, G., Austin, M. A., Grunau, B., Wittwer, L. K., Richmond, N., Morrison, L. J., Kurz, M. C., Cheskes, S., Kudenchuk, P. J., Zive, D. M., Aufderheide, T. P., Wang, H. E., Herren, H., Vaillancourt, C., Davis, D. P., Vilke, G. M. Variation in Survival After Out-of-Hospital Cardiac Arrest Between Emergency Medical Services Agencies. JAMA Cardiol. 2018;3(10):989-999. doi:10.1001/jamacardio.2018.3037

Barbic, D., Andolfatto, G., Grunau, B., Scheuermeyer, F. X., MacEwan, W., Honer, W. G., Wong, H., & Barbic, S. P. (2018) Rapid agitation control with ketamine in the emergency department (RACKED): a randomized controlled trial protocol. Trials. 2018;19(1):651. doi:10.1186/s13063-018-2992-x

Abu-laban R B, Drebit S, Lindstrom R, Chantel Archibald , Kim Eggers , Kendall Ho , Afshin Khazei, Adam Lund , Carolyn MacKinnon , Ray Markham ,Julian Marsden , Ed Martin , Jim Christenson (January 04, 2018) The British Columbia Emergency Medicine Network: A Paradigm Shift in a Provincial System of Emergency Care. Cureus 10(1): e2022. DOI: 10.7759/cureus.2022
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Tanguay-Rioux X, Grunau B, Neumar R, Tallon J, Boone R, Christenson J. Is initial rhythm in OHCA a predictor of preceding no flow time? Implications for bystander response and ECPR candidacy evaluation. Resuscitation. 2018 Jul;128:88-92. doi: 10.1016/j.resuscitation.2018.05.002. Epub 2018 May 5.

Steven C. Brooks, Sam D. Shemie, Laura Hornby , Clay Gillrie , Brian Grunau, A. Dave Nagpal, Andrew Baker, Jim Christenson , John Gill and Laurie Morrison. Barriers and opportunities related to extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest in Canada: A report from the first meeting of the Canadian ECPR Research Working Group. Canadian Journal of Emergency Medicine. Volume 20, Issue 4. July 2018. Pg 507-517.
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Ross A. Pollack, Siobhan P. Brown, Thomas Rea, Tom Aufderheide, David Barbic, Jason E. Buick, Jim Christenson, Ahamed H. Idris, Jamie Jasti, Michael Kampp, Peter Kudenchuk, Susanne May, Marc Muhr, Graham Nichol, Joseph P. Ornato, George Sopko, Christian Vaillancourt, Laurie Morrison, Myron Weisfeldt, MD and the ROC Investigators. Impact of Bystander Automated External Defibrillator Use on Survival and Functional Outcomes in Shockable Observed Public Cardiac Arrests. Circulation. 2018;137:00–00. DOI: 10.1161/CIRCULATIONAHA.117.030700

Brian Grunau, Takahisa Kawano, William Dick, Ronald Straight, Helen Connolly, Robert Schlamp, Frank X. Scheuermeyer, Christopher B Fordyce, David Barbic, John Tallon, Jim Christenson. Trends in care processes and survival following prehospital resuscitation improvement initiatives for out-of-hospital cardiac arrest in British Columbia, 2006 – 2016. Resuscitation 2018:125;118-125.

D.M. Zive, R. Schmicker, M. Daya, P. Kudenchuk, G. Nichol, J.C. Rittenberger, T. Aufderheide, Vilke, J. Christenson, J.E. Buick, K. Kaila, S. May, T. Rel, L.J. Morrison, for the ROC Investigators. Survival and variability over time from out of hospital cardiac arrest across large geographically diverse communities participating in the Resuscitation Outcomes Consortium. Resuscitation 131(2018)74-82.

2017

Kawano T, Scheuermeyer FX, Stenstrom R, Rowe BH, Grafstein E, Grunau B. Epinephrine use in older patients with anaphylaxis: Clinical outcomes and cardiovascular complications. Resuscitation. 2017;112. doi:10.1016/j.resuscitation.2016.12.020

Kawano, T., Grunau, B., Scheuermeyer, F. X., Gibo, K., Dick, W., Fordyce, C. B., Dorian, P., Stenstrom, R., Straight, R., & Christenson, J.. Prehospital sodium bicarbonate use could worsen long term survival with favorable neurological recovery among patients with out-of-hospital cardiac arrest. Resuscitation. 2017;119:63-69. doi:10.1016/j.resuscitation.2017.08.008

Salcido, D. D., Schmicker, R. H., Buick, J. E., Cheskes, S., Grunau, B., Kudenchuk, P., Leroux, B., Zellner, S., Zive, D., Aufderheide, T. P., Koller, A. C., Herren, H., Nuttall, J., Sundermann, M. L., Menegazzi, J. J. Compression-to-ventilation ratio and incidence of rearrest—A secondary analysis of the ROC CCC trial. Resuscitation. 2017;115. doi:10.1016/j.resuscitation.2017.04.007

Reynolds, J. C., Grunau, B. E., Elmer, J., Rittenberger, J. C., Sawyer, K. N., Kurz, M. C., Singer, B., Proudfoot, A., & Callaway, C. W. Prevalence, natural history, and time-dependent outcomes of a multi-center North American cohort of out-of-hospital cardiac arrest extracorporeal CPR candidates. Resuscitation. 2017;117:24-31. doi:10.1016/j.resuscitation.2017.05.024

Laurie J. Morrison, Sean M. Devlin, Michael C. Kontos, Sheldon Cheskes, Tom P. Aufderheide, Jim Christenson, Joseph P. Ornato, Ian G. Stiell, Valeria E. Raci. The association of maximum Troponin values post out-of-hospital cardiac arrest with electrocardiographic findings, cardiac reperfusion procedures and survival to discharge; A Sub-study of ROC PRIMED. RESUSCITATION. February 2017. 111:82–89

Grunau B, Taylor J, Scheuermeyer FX, Stenstrom R, Dick W, Kawano T, Barbic D, Drennan I, Christenson J. External Validation of the Universal Termination of Resuscitation Rule for Out-of-Hospital Cardiac Arrest in British Columbia. Ann Emerg Med. 2017 Mar 14. doi:10.1016/j.annemergmed.2017.01.030

Sheldon Cheskes, Robert H. Schmicker, Tom Rea, Laurie J. Morrison, Brian Grunau, Ian R. Drennan, Brian Leroux, Christian Vaillancourt, Terri A. Schmidt, Allison C. Koller, Peter Kudenchuk, Tom P. Aufderheide, Heather Herren, Katharyn H. Flickinger, Mark Charleston, Ron Straight, Jim Christenson for the ROC investigators. The Association between AHA CPR Quality Guideline Compliance and Clinical Outcomes from Out-of-Hospital Cardiac Arrest. Resuscitation 2017;116: 39–45.

Grunau B, Carrier S, Bashir J, Dick W, Harris L, Boone R, Kalla D, Scheuermeyer F, Twaites B, Straight R, Abel J, McDonald K, MacRedmond R, Agulnik D, Finkler J, MacLeod J, Christenson J, Cheung A. A comprehensive regional clinical and educational ECPR protocol decreases time to ECMO in patients with refractory out-of-hospital cardiac arrest. CJEM. 2017 Nov;19(6):424-433. doi: 10.1017/cem.2017.376. Epub 2017 Aug 16. PubMed PMID: 28810931.
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Kawano T, Grunau B, Scheuermeyer FX, Gibo K, Dick W, Fordyce CB, Dorian P, Stenstrom R, Straight R, Christenson J. Prehospital sodium bicarbonate use could worsen long term survival with favorable neurological recovery among patients with out-of-hospital cardiac arrest. Resuscitation. 2017 Oct;119:63-69. doi: 10.1016/j.resuscitation.2017.08.008. Epub 2017 Aug 10. PubMed PMID: 28802878.

Wang HE, Prince DK, Drennan IR, Grunau B, Carlbom DJ, Johnson N, Hansen M, Elmer J, Christenson J, Kudenchuk P, Aufderheide T, Weisfeldt M, Idris A, Trzeciak S, Kurz M, Rittenberger JC, Griffiths D, Jasti J, May S; Resuscitation Outcomes Consortium (ROC) Investigators. Post-resuscitation arterial oxygen and carbon dioxide and outcomes after out-of-hospital cardiac arrest. Resuscitation. 2017 Nov;120:113-118. doi: 10.1016/j.resuscitation.2017.08.244. Epub 2017 Sep 21. PubMed PMID: 28870720; PubMed Central PMCID: PMC5660655.

Steven C. Brooks, Robert H. Schmicker, Sheldon Cheskes, Jim Christenson, Alan Craig, Mohamud Daya, Peter J Kudenchuk, Graham Nichol, Dana Zive, Laurie J. Morrison, on behalf of the Resuscitation Outcomes Consortium Investigators. Variability in the initiation of resuscitation attempts by emergency medical services personnel during out-of-hospital cardiac arrest. Resuscitation 117 (2017) 102–108.

Brian Grunau, Joseph Puyat, Hubert Wong, Frank X. Scheuermeyer, Joshua C. Reynolds, Takahisa Kawano, Joel Singer, William Dick & James Christenson (2017) Gains of Continuing Resuscitation in Refractory Out-of-hospital Cardiac Arrest: A Model-based Analysis to Identify Deaths Due to Intra-arrest Prognostication, Prehospital Emergency Care, 2017: 22:2, 198-207

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